Tsunade

- Tsunade as a child. - Tsunade's full appearance. - Tsunade without her haori. - Tsunade in her shinobi outfit. 1/4 Tsunade is a fair-skinned woman with brown eyes and straight blonde hair. Her hair parts above her forehead and has shoulder-length bangs that frame her face and the rest reaches her lower back. During her childhood and through her young-adult years, she wore her hair in a high ponytail, but she later keeps it tied in two loose ponytails. The Strength of a Hundred Seal - taking the appearance of a violet diamond mark- is clearly visible on her forehead. As an adolescent, Tsunade was considered flat-chested, something which her teammate Jiraiya poked fun at. By young-adulthood however, she grew into a slender woman with noticeably large breasts and a curvaceous figure, which Jiraiya noted to be 106 centimetres; Tsunade is in fact widely regarded as the most beautiful kunoichi in the world. By her fifties, she appears much older, being heavily wrinkled and rather frail-looking (presumably from over-usage of her Creation Rebirth). However, she maintains her youthful appearance using a unique Transformation Technique. In her childhood, Tsunade wore grey mesh shirt and over it a teal-coloured kimono with short sleeves and red-lining around the collars which she secured with a blue sash. She also wore red wristbands and white wrapping over her calves with blue sandals. Tsunade often wears a grass-green haori with the kanji for "gamble" (賭, kake) on the back, inside a red circle. Underneath she wears a grey, kimono-style blouse with no sleeves, held closed by a broad, dark bluish-grey obi that matches her pants. Her blouse is closed quite low, revealing her sizeable cleavage. She wears open-toed, strapped black sandals with high heels. She has red nail polish on both her fingernails and toenails and uses a soft pink lipstick. She wore the First Hokage's necklace for many years until she gave it to Naruto.

Tsunade is the granddaughter of Hashirama Senju and Mito Uzumaki. Because Hashirama was the First Hokage of Konohagakure, Tsunade is called "Princess" (姫, Hime). Hashirama doted on Tsunade when she was very young because she was his first grandchild and found her deviance and her adoption of his own gambling habits highly amusing. Tsunade inherited his necklace when he died. After she graduated from Konoha's Academy, Tsunade was teamed with Orochimaru and Jiraiya under the leadership of Hiruzen Sarutobi. When Jiraiya failed to acquire a bell during the team's first bell test, Tsunade teased him, prompting him to criticise her flat chest. Despite this remark, Jiraiya had a certain interest in Tsunade from their first meeting, which only increased after her breasts developed. When she nearly killed him for spying on her while she bathed, he was forced to be more discreet about both his attraction to her and his interest in peeping. Tsunade's younger brother, Nawaki dreamed of someday becoming Hokage so that he could protect Konoha, their grandfather's legacy. On Nawaki's twelfth birthday, Tsunade kissed his forehead and gave him Hashirama's necklace in the hopes that it would help him achieve his dream. He died the next day, a casualty of the ongoing Second Shinobi World War, thus returning the necklace to her. Tsunade began advocating for the inclusion of medical-nin on all four-man squads in order to avoid future deaths like Nawaki's. Hiruzen, the Third Hokage, agreed with her arguments, but could not dedicate resources to the necessary implementation due to the ongoing war. Dan Katō, on the other hand, shared her views, and as their relationship developed he confided with her his dreams of becoming Hokage so that he could bring change to Konoha and protect his loved one from death. Tsunade kissed his forehead and gave him Hashirama's necklace in the hopes that it would help him achieve his dream. Although their team under Hiruzen's leadership had disbanded, Tsunade, Orochimaru, and Jiraiya continued fighting together during the Second Shinobi World War. During one such fight in Amegakure, they were the only three to survive an encounter with Hanzō, an accomplishment for which Hanzō dubbed them Konoha's "Legendary Sannin". In the aftermath of the battle, Jiraiya opted not to return to Konoha so that he could train the Ame orphans. Tsunade would go on to make her own independent contributions to the war, frequently counteracting Chiyo of Sunagakure's poisons. Although Tsunade's actions are said to have won the war for Konoha, Tsunade was unable to prevent Dan's death, and her failure to stop his severe blood loss caused her to develop haemophobia. With Dan's death, Hashirama's necklace returned to Tsunade once again, convincing some that the necklace was cursed to kill anyone who wore it other than Tsunade. Tsunade herself became convinced that achieving one's dreams was impossible and that to be Hokage was a "fool's job". She therefore left Konoha during the height of the Third Shinobi World War, taking Dan's niece, Shizune, with her to train her as a disciple. Due to her haemophobia, Tsunade retired from any direct involvement in healing or combat, instead relying on Shizune's skills whenever a need for either came up. At one point during their travels, Tsunade and Shizune encountered the Fourth Raikage A, where the latter requested her help in removing the Exploding Insect implanted in his subordinate. However, Tsunade was completely drunk and ended up falling asleep, completely forgetting about her conversation with A. After A insisted, Tsunade challenged him to an arm wrestling contest, promising to help should she lose. A managed to defeat Tsunade by using his speed rather than strength, and Tsunade complied and followed him to his subordinate's location. After Tsunade diagnoses the situation and realises that one of the insects was also inside A, she decided to conduct the surgery. However, Tsunade instead enlisted Shizune to conduct it, and once blood was splattered in her face, Tsunade left to regain her composure while Shizune performed the surgery and explained the origins of Tsunade's trauma to A and his team.