Mito Uzumaki

Mito had long, bright-red hair and large, black pupilless eyes. She wore an elaborate, high-collared kimono with the Uzushiogakure symbol on the back of the obi which was tied around her waist. Her hair was arranged in buns with hair pins in them and three clips in the front. She also wore a dark shade of red lipstick and had a rhombus marking reminiscent of the Strength of a Hundred Seal on her forehead. She also wore tags with kanji written on them in her hair decals. In her old age, her hair had grown much longer some of which she allowed to hang into her back (in the anime her hair was depicted as brown in her old age). She, however, maintained the two buns in her hair and wore a simple loose fitting kimono held closed by a simple dark-coloured obi.

The Uzumaki and Senju clans — being distant relatives — have always had close ties. Mito ended up marrying Hashirama Senju, who would help found Konohagakure and became the village's First Hokage. After Hashirama's victory against Madara Uchiha at the Valley of the End and obtaining Kurama from him, Mito sealed the tailed beast within herself, becoming its first jinchūriki. Despite the seal's strength, it almost broke when she was going through childbirth. Towards the final years of her life, it was decided that a new host for Kurama would have to be found. Kushina Uzumaki, one of Mito's clansmen, was then selected for the role due to her special chakra. Terrified by the idea of having been taken from her home to become a jinchūriki, Mito comforted Kushina, and told her that in order to counter the fox's hatred, she needed to fill herself with love. She elaborated on the topic by comparing their situation with their clan symbol and their residence, that while a spiral is two-dimensional, staying in one place, they need to be a three-dimensional helix, capable of rising by filling themselves with love. Some time after this, the beast was presumably extracted from within Mito and sealed into Kushina, resulting in Mito's death.